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Article

Drosophila Fip200 is an essential regulator of autophagy that attenuates both growth and aging.

Autophagy - 1 Aug 2013

Kim Myungjin, Park Hae Li, Park Hwan-Woo, Ro Seung-Hyun, Nam Samuel G, Reed John M, Guan Jun-Lin, Lee Jun Hee

Abstract excerpt

Autophagy-related 1 (Atg1)/Unc-51-like protein kinases (ULKs) are evolutionarily conserved proteins that play critical physiological roles in controlling autophagy, cell growth and neurodevelopment. RB1-inducible coiled-coil 1 (RB1CC1), also known as PTK2/FAK family-interacting protein of 200 kDa (FIP200) is a recently discovered binding partner of ULK1. Here we isolated the Drosophila RB1CC1/FIP200 homolog...

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Source

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Identifiers

PMID: 23819996
DOI: 10.4161/auto.24811
PMCID: PMC3748192

Genes

PTK2
ULK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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