Article
Role of FIP200 in inflammatory processes beyond its canonical autophagy function.
Biochemical Society transactions - 28 Aug 2020
Yeo Syn Kok, Wang Chenran, Guan Jun-Lin
Abstract excerpt
FIP200 (RB1CC1) is a critical regulator of canonical macroautophagy and has also emerged as a crucial regulator of selective autophagy as well as inflammatory processes. The illumination of FIP200's role in autophagy at the molecular level has been accompanied by studies demonstrating the importance of its autophagy function in physiological processes in mammals and pathological contexts such as cancer. However,...
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