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Article

Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2.

Autophagy - 1 Mar 2013

McAlpine Fiona, Williamson Leon E, Tooze Sharon A, Chan Edmond Y W

Abstract excerpt

Macroautophagy, commonly referred to as autophagy, is a protein degradation pathway that occurs constitutively in cells, but can also be induced by stressors such as nutrient starvation or protein aggregation. Autophagy has been implicated in multiple disease mechanisms including neurodegeneration and cancer, with both tumor suppressive and oncogenic roles. Uncoordinated 51-like kinase 1 (ULK1) is a critical...

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Source

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Identifiers

PMID: 23291478
DOI: 10.4161/auto.23066
PMCID: PMC3590256

Genes

ULK1
ULK2
MTOR
ZFYVE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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