Article
The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway in C. elegans.
Autophagy - 1 Feb 2011
Yang Peiguo, Zhang Hong
Abstract excerpt
Macroautophagy (hereafter referred to as autophagy) involves the formation of a closed, double membrane structure, called the autophagosome. Most of the Atg proteins that are essential for autophagosome formation are evolutionarily conserved between yeast and higher eukaryotes. The functions of some Atg proteins, however, are mediated by highly divergent proteins in mammalian cells. In this study, we identified a...
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