Article
Label-free detection of single-nucleotide polymorphisms associated with myeloid differentiation-2 using a nanostructured biosensor.
Biosensors & bioelectronics - 15 Nov 2013
Chin Yu-Ting, Liao En-Chih, Wu Chia-Che, Wang Gou-Jen, Tsai Jaw-Ji
Abstract excerpt
House dust mites are the major source of indoor allergens that are responsible for asthma. The major dust mite allergen is the group II allergen, Der p2. Myeloid differentiation-2 (MD-2) acts as an essential component in the CD14-TLR4 (toll-like receptor)/MD-2 receptor complex for Der p2 recognition. Mutations of the MD-2 associated gene on chromosome 8 degrade a human's innate responses. In this study, we report...
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