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Article

Detection of haplotype mutations of the MD-2 gene promoter associated with Der p2-induced allergy using a nanostructured biosensor.

International journal of nanomedicine - 1 Jan 2014

Chin Yu-Ting, Liao En-Chih, Wu Chia-Che, Wang Gou-Jen, Tsai Jaw-Ji

Abstract excerpt

Group 2 allergens (Der p2) have been reported to be a major cause of the human immune response to dust mite allergens. In this study, we have demonstrated for the first time the effective differentiation between haplotype mutation and normal genes in the MD-2 gene promoter using a nanostructured biosensor. A 70-mer gene fragment containing the haplotype of two single nucleotide polymorphisms in the MD-2 gene...

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Identifiers

PMID: 24648737
DOI: 10.2147/IJN.S59151
PMCID: PMC3958545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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