Effects of seven different mutations in the pho1 gene on enzymatic activity, glycosylation and secretion of acid phosphatase in Schizosaccharomyces pombe.

doi:10.1007/BF00259405

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Article

Effects of seven different mutations in the pho1 gene on enzymatic activity, glycosylation and secretion of acid phosphatase in Schizosaccharomyces pombe.

Molecular & general genetics : MGG - 1 May 1990

Schwaninger R, Dumermuth E, Schweingruber M E

Abstract excerpt

Structural gene mutants of the cell-surface glycoprotein acid phosphatase of Schizosaccharomyces pombe were analysed to define structural determinants that are responsible for enzymatic activity, N-glycosylation and secretion. All seven defined mutations cause a single amino acid substitution in...

Topics

Acid Phosphatase
Cloning, Molecular
DNA, Fungal
Genes, Fungal
Glycosylation
Mutation
Nucleotide Mapping
Schizosaccharomyces

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