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Article

Molecular and expression analysis of the negative regulators involved in the transcriptional regulation of acid phosphatase production in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Nov 1990

Madden S L, Johnson D L, Bergman L W

Abstract excerpt

The PHO80 and PHO85 gene products encode proteins necessary for the repression of transcription from the major acid phosphatase gene (PHO5) of Saccharomyces cerevisiae. The deduced amino acid sequences of these genes have revealed that PHO85 is likely to encode a protein kinase, whereas no potential function has been revealed for PHO80. We undertook several approaches to aid in the elucidation of the PHO80...

Topics

Acid Phosphatase
Chromosome Deletion
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Fungal
Genes, Fungal
Genes, Regulator
Genotype
Kinetics
Mutagenesis, Site-Directed
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

beta-Galactosidase

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Identifiers

PMID: 2122235
DOI: 10.1128/mcb.10.11.5950-5957.1990
PMCID: PMC361392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2122235-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Molecular and expression analysis of the negative regulators involved in the transcriptional regulation of acid phosphatase production in Saccharomyces cerevisiae.PMID 2122235Read ↗

Negative regulators of the PHO system of Saccharomyces cerevisiae: characterization of PHO80 and PHO85.Semantic proximity Read ↗

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Functional domains of a positive regulatory protein, PHO4, for transcriptional control of the phosphatase regulon in Saccharomyces cerevisiae.Semantic proximity Read ↗

A systematic high-throughput screen of a yeast deletion collection for mutants defective in PHO5 regulation.Semantic proximity Read ↗

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Molecular analysis of the PHO81 gene of Saccharomyces cerevisiae.Semantic proximity Read ↗

A genetic study of signaling processes for repression of PHO5 transcription in Saccharomyces cerevisiae.Semantic proximity Read ↗

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