Article
Aspartic acid 252 and asparagine 185 are essential for activity of lipid N-acetylglucosaminylphosphate transferase.
Glycobiology - 1 Dec 1997
Scocca J R, Krag S S
Abstract excerpt
A key step in the assembly of oligosaccharide-lipid intermediates in N-linked glycosylation is the transfer of N-acetylglucosamine 1-phosphate to dolichyl phosphate, catalyzed by the enzyme UDP-N-acetylglucosaminyl:dolichyl phosphate N-acetylglucosaminyl phosphoryl transferase (L-G1PT). Compariso...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Asparagine
- Aspartic Acid
- Cricetinae
- Drug Resistance, Microbial
- Gene Deletion
- Gene Expression
- Immunoblotting
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Plasmids
- Schizosaccharomyces
- Structure-Activity Relationship
- Transferases (Other Substituted Phosphate Groups)
- Tunicamycin