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Article

Interaction between PLA2R1 and HLA-DQA1 variants associates with anti-PLA2R antibodies and membranous nephropathy.

Journal of the American Society of Nephrology : JASN - 1 Jul 2013

Lv Jicheng, Hou Wanyin, Zhou Xujie, Liu Gang, Zhou Fude, Zhao Na, Hou Ping, Zhao Minghui, Zhang Hong

Abstract excerpt

Risk alleles at genome loci containing phospholipase A2 receptor 1 (PLA2R1) and HLA-DQA1 closely associate with idiopathic membranous nephropathy (IMN) in the European population, but it is unknown whether a similar association exists in the Chinese population and whether high-risk alleles promote the development of anti-PLA2R antibodies. Here, we genotyped 2132 Chinese individuals, including 1112 patients with...

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Identifiers

PMID: 23813219
DOI: 10.1681/ASN.2012080771
PMCID: PMC3736719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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