Article
The association between variants in PLA2R and HLA-DQA1 and renal outcomes in patients with primary membranous nephropathy in Western China.
BMC medical genomics - 8 May 2021
Fan Shulei, Wang Qiuxia, Wang Amanda Y, Zhang Ping, Zhong Xiang, Chen Shasha, Li Guisen, Wang Li, Wang Wei
Abstract excerpt
BACKGROUND: Both Genome-wide associations and our previous study have shown that single nucleotide polymorphisms (SNPs) of M-type phospholipase A2 receptor (PLA2R) and human leukocyte antigen complex class II HLA-DQα-chain 1 (HLA-DQA1) gene were identified to be associated with primary membranous nephropathy (PMN). However, whether these SNPs affect clinical manifestation and renal outcome for PMN patients is...
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