Article
Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan.
Journal of biomedical science - 11 Oct 2010
Liu Yu-Huei, Chen Cheng-Hsu, Chen Shih-Yin, Lin Ying-Ju, Liao Wen-Ling, Tsai Chang-Hai, Wan Lei, Tsai Fuu-Jen
Abstract excerpt
BACKGROUND: Idiopathic membranous nephropathy (IMN) is one of the most common forms of autoimmune nephritic syndrome in adults. The purpose of this study is to evaluate whether polymorphisms of PLA2R1 affect the development of IMN. METHODS: Taiwanese-Chinese individuals (129 patients with IMN and 106 healthy controls) were enrolled in this study. The selected single nucleotide polymorphisms (SNPs) in PLA2R1 were...
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