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Article

Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy.

Clinical and experimental nephrology - 1 Apr 2018

Kaga Hajime, Komatsuda Atsushi, Omokawa Ayumi, Okuyama Shin, Mori Kensuke, Wakui Hideki, Takahashi Naoto

Abstract excerpt

BACKGROUND: Several recent studies in patients with idiopathic membranous nephropathy (iMN) from Western and Asian counties showed that some single nucleotide polymorphisms (SNPs) within the PLA2R1 and HLA-DQA1 genes are significantly associated with iMN. However, there is only 1 report on analysis of PLA2R1 and HLA regions in Japanese patients with iMN. METHODS: A total of 58 patients with iMN, 26 patients with...

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PMID: 28849274
DOI: 10.1007/s10157-017-1471-0

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