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Article

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Dec 2013

Walsh Michael D, Clendenning Mark, Williamson Elizabeth, Pearson Sally-Ann, Walters Rhiannon J, Nagler Belinda, Packenas David, Win Aung K, Hopper John L, Jenkins Mark A, Haydon Andrew M, Rosty Christophe, English Dallas R, Giles Graham G, McGuckin Michael A, Young Joanne P, Buchanan Daniel D

Abstract excerpt

Mucinous differentiation is associated with both CpG island methylator phenotype and microsatellite instability in colorectal cancer. The mucinous phenotype derives from abundant expression of the colonic goblet cell mucin, MUC2, and de novo expression of gastric foveolar mucin, MUC5AC. We, there...

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Source

Identifiers

PMID: 23807779
DOI: 10.1038/modpathol.2013.101

Genes

MUC2
CDX2
BRAF
MLH1
KRAS
MSH2
MSH6
PMS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23807779-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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