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Article

A modified murine model based on hydrodynamic injection for the analysis of chronic human hepatitis B virus infection.

Molecular medicine reports - 1 Dec 2013

Qin Bo, Tu Chunyu, Zhang Bo, He Tingting, Fu Lijun, Xu Wenying

Abstract excerpt

Hepatitis B virus (HBV) is a persistent pathogen that causes acute and chronic necroinflammatory liver disease and is attributable to ~1 million deaths per year. In the present study, a conventional murine model was introduced based on the hydrodynamic injection of engineered replication‑competent HBV DNA into the tail veins of C57BL/6 mice. In a previous study, nine in‑frame ATG (start) codons in the S open...

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Source

Identifiers

PMID: 24141768
DOI: 10.3892/mmr.2013.1732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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