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Article

RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant.

Gastroenterology - 1 Mar 2005

Wu Hui-Lin, Huang Li-Rung, Huang Chuan-Chuan, Lai Hsiao-Lei, Liu Chun-Jen, Huang Yu-Tzu, Hsu Yun-Wei, Lu Cheng-Yi, Chen Ding-Shinn, Chen Pei-Jer

Abstract excerpt

BACKGROUND & AIMS: Present therapy for chronic hepatitis B attains control only in limited proportions. Small interfering RNA (siRNA) offers a new tool with potential therapeutic applications for hepatitis B virus (HBV). Given the importance of sequence identity in the effectiveness of siRNA and the heterogeneity of HBV sequences among different isolates, a short hairpin RNA (shRNA)-expressing plasmid,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15765406
DOI: 10.1053/j.gastro.2004.12.007
PMCID: PMC7094679

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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