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Article

Differential repair and replication of damaged DNA in ribosomal RNA genes in different CHO cell lines.

Journal of cellular biochemistry - 1 Jun 1990

Wauthier E L, Hanawalt P C, Vos J M

Abstract excerpt

We studied the repair of psoralen adducts in the pol I-transcribed ribosomal RNA (rRNA) genes of excision repair competent Chinese hamster ovary (CHO) cell lines, their UV sensitive mutant derivatives, and their UV resistant transformants, which express a human excision repair gene. In the parental cell line CHO-AA8, both monoadducts and interstrand crosslinks are removed efficiently from the rRNA genes, whereas...

Topics

Animals
Cell Line
Cricetinae
Cricetulus
DNA
DNA Adducts
DNA Damage
DNA Repair
DNA Replication
Furocoumarins
Humans
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Ribosomal

Restriction Mapping

Ultraviolet Rays

Source

Identifiers

PMID: 2380262
DOI: 10.1002/jcb.240430208

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2380262-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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