Deletions in the cytoplasmic domain of the polymeric immunoglobulin receptor differentially affect endocytotic rate and postendocytotic traffic.

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Article

Deletions in the cytoplasmic domain of the polymeric immunoglobulin receptor differentially affect endocytotic rate and postendocytotic traffic.

The Journal of biological chemistry - 15 Aug 1990

Breitfeld P P, Casanova J E, McKinnon W C, Mostov K E

Abstract excerpt

We have examined the function of the cytoplasmic domain of the polymeric immunoglobulin receptor (pIg-R) by producing two separate deletions in the cytoplasmic domain of the pIg-R, expressing the mutant receptors in polarized MDCK cells, and analyzing each for their effects on receptor and ligand...

Topics

Animals
Cell Line
Cell Membrane
Chromosome Deletion
Cloning, Molecular
Cytoplasm
DNA, Recombinant
Endocytosis
Immunoglobulin Fab Fragments
Kinetics
Mutation
Receptors, Immunologic
Secretory Component

Source

Open in PubMed

Identifiers

PMID: 2380185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2380185-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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