Article
A genetic variant of the atrial natriuretic peptide gene is associated with left ventricular hypertrophy in a non-diabetic population--the Malmö preventive project study.
BMC medical genetics - 24 Jun 2013
Jujić Amra, Leosdottir Margret, Östling Gerd, Gudmundsson Petri, Nilsson Peter M, Melander Olle, Magnusson Martin
Abstract excerpt
BACKGROUND: Epidemiological studies have shown considerable heritability of blood pressure, thus suggesting a role for genetic factors. Previous studies have shown an association of a single nucleotide polymorphism rs5068 in the NPPA locus gene with higher levels of circulating atrial natriuretic peptide as well as with lower intra individual blood pressure, but up to date, no association between rs5068 and...
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