Article
Natriuretic peptides and the genomics of left-ventricular hypertrophy.
Heart failure clinics - 1 Jan 2010
Dries Daniel L
Abstract excerpt
Left-ventricular hypertrophy (LVH) is one of the strongest independent predictors of cardiovascular morbidity and mortality in the general population. Although hypertension and obesity are well-established, independent risk factors for the development of LVH, they explain less than 25% to 50% of the variance of left ventricular mass (LVM) in humans. A substantial body of evidence suggests that there is a genetic...
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