Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Caenorhabditis elegans histone deacetylase hda-1 is required for morphogenesis of the vulva and LIN-12/Notch-mediated specification of uterine cell fates.

G3 (Bethesda, Md.) - 7 Aug 2013

Ranawade Ayush Vasant, Cumbo Philip, Gupta Bhagwati P

Abstract excerpt

Chromatin modification genes play crucial roles in development and disease. In Caenorhabditis elegans, the class I histone deacetylase family member hda-1, a component of the nucleosome remodeling and deacetylation complex, has been shown to control cell proliferation. We recovered hda-1 in an RNA interference screen for genes involved in the morphogenesis of the egg-laying system. We found that hda-1 mutants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans Proteins
Share to Histone Deacetylases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Morphogenesis

Share to Proto-Oncogene Proteins c-fos

Share to Receptors, Cytoplasmic and Nuclear

Share to Receptors, Notch

Share to Uterus

Source

Open in PubMed Open full text

Identifiers

PMID: 23797102
DOI: 10.1534/g3.113.006999
PMCID: PMC3737176

Genes

HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Caenorhabditis elegans histone deacetylase hda-1 is required for morphogenesis of the vulva and LIN-12/Notch-mediated specification of uterine cell fates.PMID 23797102Read ↗

Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis.Semantic proximity Read ↗

Role of C. elegans lin-40 MTA in vulval fate specification and morphogenesis.Semantic proximity Read ↗

The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells.Semantic proximity Read ↗

Vulval developmentSemantic proximity Read ↗

Two<i>C. elegans</i>histone methyltransferases repress<i>lin-3</i>EGF transcription to inhibit vulval developmentSemantic proximity Read ↗

Genetic control of vulval development in Caenorhabditis briggsae.Semantic proximity Read ↗

Identification of Wnt Pathway Target Genes Regulating the Division and Differentiation of Larval Seam Cells and Vulval Precursor Cells in Caenorhabditis elegans.Semantic proximity Read ↗

A Network of Chromatin Factors Is Regulating the Transition to Postembryonic Development in Caenorhabditis elegans.Semantic proximity Read ↗

The C. elegans Mi-2 chromatin-remodelling proteins function in vulval cell fate determination.Semantic proximity Read ↗

NuRD chromatin remodeling is required to repair exogenous DSBs in the <i>Caenorhabditis elegans</i> germlineSemantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-14 coordinates temporal progression and maturation in the egg-laying system.Semantic proximity Read ↗

Transcriptional repression of Hox genes by C. elegans HP1/HPL and H1/HIS-24.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.