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Article

The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells.

Development (Cambridge, England) - 1 Dec 1999

Newman A P, Acton G Z, Hartwieg E, Horvitz H R, Sternberg P W

Abstract excerpt

The Caenorhabditis elegans hermaphrodite egg-laying system comprises several tissues, including the uterus and vulva. lin-11 encodes a LIM domain transcription factor needed for certain vulval precursor cells to divide asymmetrically. Based on lin-11 expression studies and the lin-11 mutant phenotype, we find that lin-11 is also required for C. elegans uterine morphogenesis. Specifically, lin-11 is expressed in...

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PMID: 10556057
DOI: 10.1242/dev.126.23.5319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The lin-11 LIM domain transcription factor is necessary for morphogenesis of C. elegans uterine cells.PMID 10556057Read ↗

Tissue-specific regulation of the LIM homeobox gene lin-11 during development of the Caenorhabditis elegans egg-laying system.Semantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-29 coordinates the vulval-uterine-epidermal connections.Semantic proximity Read ↗

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The anchor cell initiates dorsal lumen formation during C. elegans vulval tubulogenesis.Semantic proximity Read ↗

Caenorhabditis elegansHOM-C Genes Regulate the Response of Vulval Precursor Cells to Inductive SignalSemantic proximity Read ↗

Heterochronic genes control cell cycle progress and developmental competence of C. elegans vulva precursor cells.Semantic proximity Read ↗

Caenorhabditis elegans histone deacetylase hda-1 is required for morphogenesis of the vulva and LIN-12/Notch-mediated specification of uterine cell fates.Semantic proximity Read ↗

The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins.Semantic proximity Read ↗

Spatial and molecular cues for cell outgrowth during C. elegans uterine development.Semantic proximity Read ↗

Vulva morphogenesis involves attraction of plexin 1-expressing primordial vulva cells to semaphorin 1a sequentially expressed at the vulva midline.Semantic proximity Read ↗

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans.Semantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-14 coordinates temporal progression and maturation in the egg-laying system.Semantic proximity Read ↗

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