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Article

Functional requirement for histone deacetylase 1 in Caenorhabditis elegans gonadogenesis.

Molecular and cellular biology - 1 May 2002

Dufourcq Pascale, Victor Martin, Gay Frédérique, Calvo Dominica, Hodgkin Jonathan, Shi Yang

Abstract excerpt

Histone acetylation and deacetylation have been implicated in the regulation of gene expression. Molecular studies have shown that histone deacetylases (HDACs) function as transcriptional repressors. However, very little is known about their roles during development in multicellular organisms. We previously demonstrated that inhibition of maternal and zygotic expression of histone deacetylase 1 (HDA-1) causes...

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Identifiers

PMID: 11940660
DOI: 10.1128/MCB.22.9.3024-3034.2002
PMCID: PMC133761

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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