Article
Microfluidics-based EGFR mutation detection and its implication in the resource-limited clinical setting.
International journal of experimental pathology - 1 Jun 2024
Joshi Pradnya, Gogte Prachi, Pai Trupti, Gurav Mamta, Dhanawade Dipika, Karnik Nupur, Deshpande Gauri, Kaushal Rajiv, Shetty Omshree
Abstract excerpt
Management of lung cancer today obligates a mutational analysis of the epidermal growth factor receptor (EGFR) gene particularly when Tyrosine Kinase Inhibitor (TKI) therapy is being considered as part of prognostic stratification. This study evaluates the performance of automated microfluidics-based EGFR mutation detection and its significance in clinical diagnostic settings. Formalin-fixed, paraffin-embedded...
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