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Article

EGFR mutation detection of lung circulating tumor cells using a multifunctional microfluidic chip.

Talanta - 1 Apr 2021

Wang Yanmin, Gao Wanlei, Wu Man, Zhang Xiaofen, Liu Wei, Zhou Yang, Jia Chunping, Cong Hui, Chen Xiang, Zhao Jianlong

Abstract excerpt

Microfluidics has become a reliable platform for circulating tumor cells (CTCs) detection because of its high integration, small size, low consumption of reagents and rapid response. Here, we developed a multifunctional microfluidic device consists of three parts, including CTCs capture area, single-layer membrane valves area, and microcavity nucleic acid detection and analysis region based on digital polymerase...

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Identifiers

PMID: 33592778
DOI: 10.1016/j.talanta.2020.122057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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