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Article

Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors.

Chemistry & biology - 20 Jun 2013

Nix Matthew A, Kaelin Christopher B, Ta Tina, Weis Allison, Morton Gregory J, Barsh Gregory S, Millhauser Glenn L

Abstract excerpt

The β-defensins are a class of small, cationic proteins first recognized as antimicrobial components of the innate and adaptive immune system. More recently, one of the major β-defensins produced in skin, β-defensin 3, has been discovered to function as a melanocortin receptor ligand in vivo and...

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Source

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Identifiers

PMID: 23790489
DOI: 10.1016/j.chembiol.2013.04.015
PMCID: PMC3714013

Genes

AGRP
ASIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23790489-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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