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Article

Determining receptor-ligand interaction of human galanin receptor type 3.

Neurochemistry international - 1 Dec 2010

Runesson Johan, Sollenberg Ulla E, Jurkowski Wiktor, Yazdi Samira, Eriksson Einar E, Elofsson Arne, Langel Ulo

Abstract excerpt

Galanin is a neuropeptide found throughout the central and peripheral nervous systems of a wide range of species, ranging from human and mouse to frog and tuna. Galanin mediates its physiological roles through three receptors (GalR1-3), all members of the G-protein coupled receptor family. In mapping these roles, receptor subtype selective ligands are crucial tools. To facilitate the ligand design, data on...

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PMID: 20817064
DOI: 10.1016/j.neuint.2010.08.018

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