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Article

Pharmacological characterization of three chicken melanocortin-3 receptor mutants.

Domestic animal endocrinology - 1 Jan 2021

Zhang H-J, Cui Z-H, Liu M, Min T-Q, Xiao X, Wang Z-Q, Tao Y-X

Abstract excerpt

The melanocortin-3 receptor (MC3R) is a G protein-coupled receptor and potentially important in production traits. Three naturally occurring mutations (M54L, G104S, and L151R) in chicken MC3R (cMC3R) were reported previously to be associated with production traits. Here, we inserted the full-length cMC3R coding sequence into pcDNA3.1(+) and generated the 3 mutations by site-directed mutagenesis. The total and...

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Identifiers

PMID: 32841887
DOI: 10.1016/j.domaniend.2020.106507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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