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Article

Chimeras of the agouti-related protein: insights into agonist and antagonist selectivity of melanocortin receptors.

Peptides - 1 Oct 2005

Jackson Pilgrim J, Yu Bin, Hunrichs Benjamin, Thompson Darren A, Chai Biaoxin, Gantz Ira, Millhauser Glenn L

Abstract excerpt

The specific melanocortin receptors, MC3R and MC4R, are directly linked to metabolism and body weight control. These receptors are activated by the peptide hormone alpha-MSH and antagonized by the agouti-related protein (AGRP). Whereas alpha-MSH acts broadly on most members of the MCR family (wit...

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Source

Identifiers

PMID: 16009463
DOI: 10.1016/j.peptides.2004.12.036

Genes

AGRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16009463-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Chimeras of the agouti-related protein: insights into agonist and antagonist selectivity of melanocortin receptors.PMID 16009463Read ↗

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