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Article

Influence of TSPO genotype on 11C-PBR28 standardized uptake values.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Aug 2013

Yoder Karmen K, Nho Kwangsik, Risacher Shannon L, Kim Sungeun, Shen Li, Saykin Andrew J

Abstract excerpt

UNLABELLED: (11)C-PBR28 binds to the high-affinity state of the translocator protein 18 kDa (TSPO). A single-nucleotide polymorphism (rs6971) within the human TSPO gene determines the affinity state of the TSPO. The rs6971 genotype determines whether individuals express the high-, low-, or mixed-affinity phenotype of TSPO. The rs6971 genotype corresponds to in vivo (11)C-PBR28 binding, as measured quantitatively...

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Source

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Identifiers

PMID: 23785173
DOI: 10.2967/jnumed.112.118885
PMCID: PMC3740346

Genes

TSPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of TSPO genotype on 11C-PBR28 standardized uptake values.PMID 23785173Read ↗

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