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Endothelial adherens junctions at a glance

1 Jan 2013

Abstract excerpt

Adherens junctions have an important role in the control of vascular permeability. These structures are located at cell-to-cell contacts, mediate cell adhesion and transfer intracellular signals. Adhesion is mediated by cadherins, which interact homophilically in trans and form lateral interactions in cis. VE-cadherin (also known as CDH5 and CD144) is the major component of endothelial adherens junctions and is...

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PMID: 23781019
DOI: 10.1242/jcs.124529

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