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Article

Endothelial cell disease: emerging knowledge from cerebral cavernous malformations

16 Feb 2017

Abstract excerpt

PURPOSE OF REVIEW: Endothelial cells dysfunctions are crucial determinants of several human diseases. We review here the most recent reports on endothelial cell defects in cerebral cavernous malformations (CCMs), particularly focusing on adherens junctions. CCM is a vascular disease that affects specifically the venous microvessels of the central nervous system and which is caused by loss-of-function mutation in...

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PMID: 28212190
DOI: 10.1097/moh.0000000000000338

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