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Article

Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway.

Langenbeck's archives of surgery - 1 Aug 2013

Arnesen Thomas, Glomnes Nina, Strømsøy Siri, Knappskog Stian, Heie Anette, Akslen Lars A, Grytaas Marianne, Varhaug Jan Erik, Gimm Oliver, Brauckhoff Michael

Abstract excerpt

BACKGROUND: Primary aldosteronism (PA) is a frequent cause (about 10 %) of hypertension. Some cases of PA were recently found to be caused by mutations in the potassium channel KCNJ5. Our objective was to determine the mutation status of KCNJ5 and seven additional candidate genes for tumorigenesis: YY1, FZD4, ARHGAP9, ZFP37, KDM5C, LRP1B, and PDE9A and, furthermore, the surgical outcome of PA patients who...

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Source

Identifiers

PMID: 23778974
DOI: 10.1007/s00423-013-1093-2

Genes

KCNJ5
ARHGAP9
FZD4
ZFP37

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway.PMID 23778974Read ↗

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