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Article

Mutations in KCNJ5 determines presentation and likelihood of cure in primary hyperaldosteronism.

ANZ journal of surgery - 1 Apr 2015

Ip Julian C Y, Pang Tony C Y, Pon Cindy K, Zhao Jing Ting, Sywak Mark S, Gill Anthony J, Soon Patsy S, Sidhu Stan B

Abstract excerpt

INTRODUCTION: Primary hyperaldosteronism (PA) is a common cause of secondary hypertension. Two recurrent mutations (G151R and L168R) in the potassium channel gene KCNJ5 have been identified that affect the Kir3.4 potassium channel found in the cells of the zona glomerulosa of the adrenal gland. The aim of this study was to determine the prevalence of KCNJ5 mutations in an Australian cohort of patients and to...

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Share to Adrenal Cortex Neoplasms
Share to Adrenal Hyperplasia, Congenital

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Adrenocortical Adenoma

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Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

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Source

Identifiers

PMID: 24274318
DOI: 10.1111/ans.12470

Genes

KCNJ5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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