Novel genes in primary aldosteronism.

Abstract excerpt

PURPOSE OF REVIEW: Novel high-throughput genetic techniques have increased the pace of discoveries in the field of primary aldosteronism. Mutations in the potassium channel gene KCNJ5 are a cause of familial and sporadic forms of primary aldosteronism with around 30-40% of aldosterone-producing adenomas being affected by somatic mutations. RECENT FINDINGS: Exome sequencing of tumors without KCNJ5 mutations...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adrenal Cortex Neoplasms
• Share to Adrenocortical Adenoma
• Share to Aldosterone