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Article

Evolution of a higher intracellular oxidizing environment in Caenorhabditis elegans under relaxed selection.

PloS one - 1 Jan 2013

Joyner-Matos Joanna, Hicks Kiley A, Cousins Dustin, Keller Michelle, Denver Dee R, Baer Charles F, Estes Suzanne

Abstract excerpt

We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for which nuclear genome base substitution and GC-TA transversion...

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PMID: 23776511
DOI: 10.1371/journal.pone.0065604
PMCID: PMC3679170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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