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Article

Mutational biases and selection in mitochondrial genomes: insights from a comparative analysis of natural and laboratory populations of Caenorhabditis elegans.

G3 (Bethesda, Md.) - 4 Mar 2026

Schifano Alexandre, Bergthorsson Ulfar, Katju Vaishali

Abstract excerpt

Spontaneous mutations display biases in their relative frequencies with important consequences for genome structure and composition. While laboratory studies have provided important insights into the spontaneous mutation spectrum, laboratory environments for optimal growth may engender biases that are not representative of natural populations. We analyzed the mitochondrial genomes of 1,524 Caenorhabditis elegans...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41460769
DOI: 10.1093/g3journal/jkaf310
PMCID: PMC12958816

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