Article
Evolution of the rate, molecular spectrum, and fitness effects of mutation under minimal selection in Caenorhabditis elegans.
Genetics - 6 May 2026
Saber Sayran, Rifat Md Monjurul Islam, Rahimi Fahimeh, Snyder Michael, Singh Amber, Eickwort Benjamin, Newhall Yell, Rajaei Moein, Saxena Ayush Shekhar, Tanny Robyn E, Katju Vaishali, Andersen Erik C, Zhou Juannan, Baer Charles F
Abstract excerpt
The rate, molecular spectrum, and fitness effects of mutations vary at all levels of the biological hierarchy, from within individual genomes to among taxonomic domains. Understanding the evolutionary factors underpinning that variation is of fundamental importance to biology. Accurate quantification of the properties of mutations requires that other evolutionary forces, especially natural selection, be minimized...
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