Article
Adaptive Evolution under Extreme Genetic Drift in Oxidatively Stressed Caenorhabditis elegans.
Genome biology and evolution - 1 Nov 2017
Christy Stephen F, Wernick Riana I, Lue Michael J, Velasco Griselda, Howe Dana K, Denver Dee R, Estes Suzanne
Abstract excerpt
A mutation-accumulation (MA) experiment with Caenorhabditis elegans nematodes was conducted in which replicate, independently evolving lines were initiated from a low-fitness mitochondrial electron transport chain mutant, gas-1. The original intent of the study was to assess the effect of electron transport chain dysfunction involving elevated reactive oxygen species production on patterns of spontaneous germline...
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