Article
Differential splicing, disease and drug targets.
Infectious disorders drug targets - 1 Dec 2008
Villate O, Rastrojo A, López-Díez R, Hernández-Torres F, Aguado B
Abstract excerpt
Genome complexity and diversity can be due to Alternative Splicing (AS), a process by which one gene can generate multiple mRNA isoforms and then several proteins. This is part of a normal process of variation on an individual, and when it is disrupted or modified, may trigger disease. To date, t...
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