Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential splicing, disease and drug targets.

Infectious disorders drug targets - 1 Dec 2008

Villate O, Rastrojo A, López-Díez R, Hernández-Torres F, Aguado B

Abstract excerpt

Genome complexity and diversity can be due to Alternative Splicing (AS), a process by which one gene can generate multiple mRNA isoforms and then several proteins. This is part of a normal process of variation on an individual, and when it is disrupted or modified, may trigger disease. To date, there are many pathologies described due to the effects of altered splicing isoforms, and effort is focused on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Anti-Infective Agents
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infections

Share to Mutation

Share to RNA, Messenger

Source

Identifiers

PMID: 19075799
DOI: 10.2174/187152608786734188

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential splicing, disease and drug targets.PMID 19075799Read ↗

Alternative Splicing and Isoforms: From Mechanisms to DiseasesSemantic proximity Read ↗

[Alternative splicing--principles, functional consequences and therapeutic implications].Semantic proximity Read ↗

Alternative Splicing in Genetic Diseases: Improved Diagnosis and Novel Treatment Options.Semantic proximity Read ↗

Pre-mRNA splicing-associated diseases and therapiesSemantic proximity Read ↗

mRNA transcript diversity creates new opportunities for pharmacological intervention.Semantic proximity Read ↗

Genomics of alternative splicing: evolution, development and pathophysiology.Semantic proximity Read ↗

Targeting RNA splicing for disease therapySemantic proximity Read ↗

Targeting Splicing in the Treatment of Human DiseaseSemantic proximity Read ↗

RNA splicing: disease and therapy.Semantic proximity Read ↗

Regulating Divergent Transcriptomes through mRNA Splicing and Its Modulation Using Various Small Compounds.Semantic proximity Read ↗

Splice modulating therapies for human disease.Semantic proximity Read ↗

Aberrant RNA splicing as the molecular basis of some pathogenic variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.