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Article

Analysis of hepatitis B virus genotyping and drug resistance gene mutations based on massively parallel sequencing.

Journal of virological methods - 1 Nov 2013

Han Yingxin, Zhang Yinxin, Mei Yanhua, Wang Yuqi, Liu Tao, Guan Yanfang, Tan Deming, Liang Yu, Yang Ling, Yi Xin

Abstract excerpt

Drug resistance to nucleoside analogs is a serious problem worldwide. Both drug resistance gene mutation detection and HBV genotyping are helpful for guiding clinical treatment. Total HBV DNA from 395 patients who were treated with single or multiple drugs including Lamivudine, Adefovir, Entecavir, Telbivudine, Tenofovir and Emtricitabine were sequenced using the HiSeq 2000 sequencing system and validated using...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Viral

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Source

Identifiers

PMID: 23773806
DOI: 10.1016/j.jviromet.2013.06.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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