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Article

Development of a novel DNA sequencing method not only for hepatitis B virus genotyping but also for drug resistant mutation detection.

BMC medical genomics - 1 Jan 2013

Wang Fanjun, Lu Lili, Yu Changshun, Lv Zhanwu, Luo Xuelian, Wan Chao, Hu Zhaohui, Zhu Qinyi, Deng Youping, Zhang Chuyu

Abstract excerpt

BACKGROUND: In HBV-infected patients, different genotypes of the hepatitis B virus influence liver disease progression and response to antiviral therapy. Moreover, long-term antiviral therapy will eventually select for drug-resistant mutants. Detection of mutations associated to antiviral therapy and HBV genotyping are essential for monitoring treatment of chronic hepatitis B patients. RESULTS: In this study, a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Viral

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Source

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Identifiers

PMID: 23369292
DOI: 10.1186/1755-8794-6-S1-S15
PMCID: PMC3552692

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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