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[High throughput detection of drug-resistance gene mutations in HBV using MALDI-TOF mass spectrometry].

Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Oct 2008

Zhou Bo-ping, Zhang Hong-mei, Li Xiao-he, Yuan Jing, Li Wei, Xu Liu-mei, Wang Huo-sheng, Chen Xin-chun, Ding Chun-ming

Abstract excerpt

OBJECTIVE: To develop a high-throughput clinical method on drug-resistance gene mutations of HBV using MALDI-TOF-MS. METHOD: Using MassArray Assay Design software designed the iPLEX primers and followed the iPLEX instruction for amplification, SAP reaction, primer extenction, desalination, dispensing, MALDI-TOF-MS screening and data analysis of the gene mutation locus. 138 serum samples of chronic HBV patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19469172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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