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Article

Clinical utility of KRAS and BRAF mutations in a cohort of patients with colorectal neoplasms submitted for microsatellite instability testing.

Clinical colorectal cancer - 1 Sept 2013

Cushman-Vokoun Allison M, Stover Daniel G, Zhao Zhiguo, Koehler Elizabeth A, Berlin Jordan D, Vnencak-Jones Cindy L

Abstract excerpt

BACKGROUND: Molecular analysis has become important in colorectal carcinoma (CRC) evaluation. Alterations in KRAS, BRAF, or mismatch repair (MMR) genes may determine therapeutic response or define a hereditary cancer syndrome. Correlation of DNA studies with clinical findings will further clarify the clinical utility of these markers. PATIENTS AND METHODS: A retrospective study was performed on 111...

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Identifiers

PMID: 23773459
DOI: 10.1016/j.clcc.2013.04.005
PMCID: PMC4090139

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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