Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between genetic variation in the ABCB1 gene and switching, discontinuation, and dosage of antidepressant therapy: results from the Rotterdam Study.

Journal of clinical psychopharmacology - 1 Aug 2013

Noordam Raymond, Aarts Nikkie, Hofman Albert, van Schaik Ron H N, Stricker Bruno H, Visser Loes E

Abstract excerpt

The objective of this study was to investigate whether polymorphisms in the ABCB1 gene were associated with switching, with discontinuation of antidepressants within 45 days after starting therapy, and/or with dose change in a large prospective population-based cohort study. Between April 1, 1991, and December 31, 2007, there were 1257 incident users of antidepressants with known ABCB1 genotypes (1236C>T,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Depression

Share to Drug Substitution

Share to Logistic Models

Share to Netherlands

Share to Odds Ratio

Source

Identifiers

PMID: 23771194
DOI: 10.1097/JCP.0b013e318291c07b

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between genetic variation in the ABCB1 gene and switching, discontinuation, and dosage of antidepressant therapy: results from the Rotterdam Study.PMID 23771194Read ↗

Influence of the CYP2D6*4 polymorphism on dose, switching and discontinuation of antidepressants.Semantic proximity Read ↗

The SLCO1B1 c.521T>C polymorphism is associated with dose decrease or switching during statin therapy in the Rotterdam Study.Semantic proximity Read ↗

Antidepressant switching as a proxy phenotype for drug non-response: investigating clinical, demographic and genetic characteristicsSemantic proximity Read ↗

Antidepressant Switching as a Proxy Phenotype for Drug Nonresponse: Investigating Clinical, Demographic, and Genetic CharacteristicsSemantic proximity Read ↗

The clinical application of ABCB1 genotyping in antidepressant treatment: a pilot study.Semantic proximity Read ↗

Influence of eight ABCB1 polymorphisms on antidepressant response in a prospective cohort of treatment-free Russian patients with moderate or severe depression: An explorative psychopharmacological study with naturalistic design.Semantic proximity Read ↗

Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy.Semantic proximity Read ↗

ABCB1 C1236T, G2677TA and C3435T Genetic Polymorphisms and Antidepressant Response Phenotypes: Results from a Portuguese Major Depressive Disorder Cohort.Semantic proximity Read ↗

ABCB1 (MDR1) gene polymorphisms are associated with the clinical response to paroxetine in patients with major depressive disorder.Semantic proximity Read ↗

ABCB1 gene variants influence tolerance to selective serotonin reuptake inhibitors in a large sample of Dutch cases with major depressive disorder.Semantic proximity Read ↗

Association of ABCB1 gene variants, plasma antidepressant concentration, and treatment response: Results from a randomized clinical study.Semantic proximity Read ↗

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocolSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.