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Article

Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease.

Nucleic acids research - 1 Aug 2013

Wang Tianyu, Sun Han-Li, Cheng Fang, Zhang Xian-En, Bi Lijun, Jiang Tao

Abstract excerpt

Members of the DnaQ superfamily are major 3'-5' exonucleases that degrade either only single-stranded DNA (ssDNA) or both ssDNA and double-stranded DNA (dsDNA). However, the mechanism by which dsDNA is recognized and digested remains unclear. Exonuclease X (ExoX) is a distributive DnaQ exonuclease that cleaves both ssDNA and dsDNA substrates. Here, we report the crystal structures of Escherichia coli ExoX in...

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Source

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Identifiers

PMID: 23771145
DOI: 10.1093/nar/gkt495
PMCID: PMC3753628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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