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Article

Use of ancestral haplotypes in genome-wide association studies.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Druet Tom, Farnir Frédéric

Abstract excerpt

We herein present a haplotype-based method to perform genome-wide association studies. The method relies on hidden Markov models to describe haplotypes from a population as a mosaic of a set of ancestral haplotypes. For a given position in the genome, haplotypes deriving from the same ancestral haplotype are also likely to carry the same risk alleles. Therefore, the model can be used in several applications such...

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PMID: 23756899
DOI: 10.1007/978-1-62703-447-0_15

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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