Article
Neuregulin signaling pathway in smoking behavior.
Translational psychiatry - 22 Aug 2017
Gupta R, Qaiser B, He L, Hiekkalinna T S, Zheutlin A B, Therman S, Ollikainen M, Ripatti S, Perola M, Salomaa V, Milani L, Cannon T D, Madden P A F, Korhonen T, Kaprio J, Loukola A
Abstract excerpt
Understanding molecular processes that link comorbid traits such as addictions and mental disorders can provide novel therapeutic targets. Neuregulin signaling pathway (NSP) has previously been implicated in schizophrenia, a neurodevelopmental disorder with high comorbidity to smoking. Using a Finnish twin family sample, we have previously detected association between nicotine dependence and ERBB4 (a neuregulin...
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