Article
Activity of human papillomavirus type 16 P97 promoter in immortal and tumorigenic human oral keratinocytes.
International journal of oncology - 1 Oct 1998
Kook J K, Kim J H, Min B M
Abstract excerpt
We previously immortalized normal human oral keratinocytes (NHOK) by transfection with cloned human papillomavirus type 16 (HPV-16) genome and converted these immortalized cells to tumorigenic cells with chemical carcinogens. Since the tumorigenic cells expressed higher level of HPV-16 E6/E7 tran...
Topics
- Base Sequence
- Binding Sites
- CCAAT-Enhancer-Binding Proteins
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Chloramphenicol O-Acetyltransferase
- DNA, Viral
- DNA-Binding Proteins
- Enhancer Elements, Genetic
- Gene Expression
- Gene Expression Regulation
- Gene Expression Regulation, Neoplastic
- Genes, Reporter
- Humans
- Keratinocytes
- Mouth Mucosa
- Mutation
- NFI Transcription Factors