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Overexpression of <scp>DNA </scp><i>polymerase iota</i> (<scp><i>Polι</i></scp>) in esophageal squamous cell carcinoma

17 Apr 2012

Abstract excerpt

The present study investigated the transcriptional regulation of low-fidelity translesion DNA synthesis (TLS) polymerases in human esophageal carcinoma. Significantly higher mRNA expression of polymerase zeta (Polξ), RAD18, polymerase iota (Polι), and polymerase kappa (Polκ) was found in esophageal carcinomas. The increased expression of Polι in tumor samples was further confirmed by immunohistochemistry. The...

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PMID: 22509890
DOI: 10.1111/j.1349-7006.2012.02309.x

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Overexpression of <scp>DNA </scp><i>polymerase iota</i> (<scp><i>Polι</i></scp>) in esophageal squamous cell carcinomaPMID 22509890Read ↗

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